Match the lot before interpreting the result
A certificate of analysis (CoA) is a record of results for a specified sample or batch. Start with the compound name, lot identifier and document date. A report for another batch, or an undated image with no sample identifier, cannot establish the results for the vial you are considering.
WHO laboratory guidance describes batch-specific records that identify the sample and testing laboratory, refer to the specification, report results and limits, and identify an authorised signatory. Use that structure to ask precise questions when a document is incomplete.
A supplier-issued document and a report issued by an independent testing laboratory have different provenance. Check which one you have. A laboratory name or logo is not enough to establish that it issued a particular report; ask for a report reference and a way to confirm its origin where needed.
Four questions a purity number cannot answer alone
| Question | What to look for | What to avoid assuming |
|---|---|---|
| Identity | A named identity test and its result for the lot. | A purity percentage by itself does not identify the compound. |
| Purity | The analytical method, reported impurities and result basis. | A chromatographic percentage is not a complete account of every substance in the vial. |
| Peptide content | A quantitative assay, units and stated calculation basis. | The catalogue label or purity percentage does not prove a measured mass of peptide per vial. |
| Microbiological properties | The specific microbiological or endotoxin tests actually reported. | Chemical purity does not establish sterility, or suitability for human or veterinary use. |
The EMA synthetic-peptide guideline treats identification, purity, assay/content, water, counter-ion content and microbiological controls as distinct considerations. It also discusses the limits of methods when impurities are not separated. This is why an isolated “99%” claim is not a substitute for the underlying specification and report.
These regulatory references concern pharmaceutical analysis. They are background for understanding documents, not evidence that HeartPep products meet pharmaceutical specifications, have regulatory approval or are suitable for administration.
A document-review checklist
- Traceability: can the compound name, lot and sample reference be matched to the material that will be supplied?
- Dates: when was the sample tested, and is an expiry or retest date stated where relevant?
- Issuer: who performed the analysis, who issued the document and who authorised it?
- Method and limits: are the test names, method references, acceptance limits, units and actual results present?
- Scope: which required properties were tested, and which remain unreported? Record missing results as unknown.
- Fit for the study: do the available documents answer the requirements set by your laboratory? Let the responsible researcher decide whether further evidence is necessary.
Keep the original document with your procurement record. A catalogue description, molecule illustration, published paper or seller summary describes something different from the tested sample.
What to request from HeartPep
Use the product enquiry form with the compound, SKU, vial quantity and any documentation requirements. Ask whether a report is available for the exact lot proposed for supply, who issued it and which tests it covers. If the lot is not yet allocated, ask for that limitation to be made clear.
HeartPep does not claim that the catalogue itself provides independently verified batch purity, peptide content or sterility. If your study needs a specific report, request and assess it before placing an order. A linked research paper does not verify a commercial batch.
Next: compare catalogue quantities and prices, or read how ordering and documentation work.